Webba platinum-containing chemotherapy in the neoadjuvant/adjuvant, locally advanced or metastatic setting. (1) This indication is approved under accelerated approval based on … Webb23 jan. 2024 · Effective and well tolerated treatment for platinum-resistant ovarian cancer remains a substantial unmet need. Despite the introduction of targeted and …
pembrolizumab (KEYTRUDA) FDA
A dose-limiting side effect is a side effect that’s serious enough to prevent doctors from increasing the dose of the drug further. The dose-limiting side effect of cisplatin is nephrotoxicity, the deterioration of your kidney function. For carboplatin, it’s myelosuppression or reduced activity of bone marrow activity that … Visa mer The first platinum-based chemotherapy drug, cisplatin, was approved for use by the FDA in 1978Trusted Source. Researchers are continuing to examine newer drugs that may … Visa mer Platinum-based chemotherapy drugs can cause serious complications, such as cognitive changes or cardiovascular problems. Your doctor may recommend lowering your dose or … Visa mer According to the American Cancer SocietyTrusted Source, it’s generally not recommended to receive a vaccine during chemotherapy or radiation treatment. The exception is the flu … Visa mer Researchers are continuing to examine whether platinum-based chemotherapy is safe for people who are pregnant or breastfeeding. In a … Visa mer roll film washer
Tecentriq European Medicines Agency
Webb23 jan. 2024 · Effective and well tolerated treatment for platinum-resistant ovarian cancer remains a substantial unmet need. Despite the introduction of targeted and immunological therapies for its management, platinum-based chemotherapy with carboplatin or cisplatin remains the backbone of treatment. Although up to 25% of women with ovarian cancer … Webb16 mars 2024 · Figure 3 Association of HRD with disease-free survival (DFS)among patients with TNBC receiving adjuvant chemotherapy in the surgical cohort.(A) DFS of HRD+/− patients with TNBC receiving platinum-containing in comparison to platinum-free chemotherapy.HRD+ was defined by an HRD score ≥ 30 and/or deleterious mutations in … Webb16 feb. 2024 · In this phase III study, the investigators enrolled patients who had disease progression after first-line platinum-containing chemotherapy, regardless of PD-L1 status. Women were randomly assigned (1:1) to receive cemiplimab (350 mg every 3 weeks) or the investigator’s choice of single-agent chemotherapy. The primary endpoint was OS. roll film for automatic shoe cover machine