Webnausea, vomiting, diarrhea; fever; headache, dizziness, drowsiness, tiredness; muscle weakness, pain in your arms or legs; problems with balance or muscle movement; … WebAug 22, 2024 · Atorvastatin has many different interactions. The most common impact of these interactions is a higher risk of atorvastatin side effects, like muscle pain. Some of …
rifampin oral and atorvastatin oral Drug Interactions - RxList
WebCoadministration has not been studied but based on metabolism and clearance, a clinically significant interaction is unlikely. Abacavir can be administered with sofosbuvir/velpatasvir and no dose alteration is required. ... Coadministration of atorvastatin (40 mg, single dose) and sofosbuvir/velpatasvir (400/100 mg, once daily) was studied in ... WebThe antituberculosis drug rifampicin (rifampin) induces a number of drug-metabolising enzymes, having the greatest effects on the expression of cytochrome P450 (CYP) 3A4 in … frances plankey
Rifampin Interactions Checker - Drugs.com
WebJun 20, 2024 · Atorvastatin 61: HVs: 40 mg, oral, MD (21 days) 0.46: 0.76: 100 mg t.i.d., 10 days, oral ... P-gp, MRP2, and BCRP) in addition to OATP transporters, the outcomes of interactions between rifampicin and the statins cannot be completely ascribed to OATP induction. 81 The comparative potential for inhibition and induction of OATP transporters … WebThe interaction of atorvastatin with rifampin is interesting because it is time-dependent and caused by a dual interaction mechanism. One dose of concomitant rifampin resulted in … WebJun 16, 2014 · In the past, this column has described drug interactions that may occur with statins. 1 The majority of these interactions have been based on precipitant drugs inhibiting the metabolism (usually via CYP3A4) of the statin. Since then, new statins (pitavastatin [Livalo] and rosuvastatin [Crestor]) have been approved for use. frances perkins and the triangle factory fire